Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ TCS 2314
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CAS: 317353-73-4 Molecular Formula: C28H34N4O6
| CAS | 317353-73-4 |
|---|---|
| Molecular Formula | C28H34N4O6 |
Tocris Bioscience™ Cediranib
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Potent inhibitor of VEGFR, PDGFR and FGFR
| Target | VEGF Receptor Inhibitors |
|---|---|
| CAS | 288383-20-0 |
| Purity | 0.98 |
| Chemical Name or Material | 4-[(4-Fluoro-2-methyl-1 H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]quinazoline |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H27FN4O3 |
Tocris Bioscience™ Silodosin
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Selective α1A adrenoceptor antagonist (Ki = 0.036 nM)
| CAS | 160970-54-7 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H32F3N3O4 |
| Formula Weight | 495.53 |
Tocris Bioscience™ Salbutamol hemisulfate
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CAS: 51022-70-9 Molecular Formula: C13H23NO7S
| CAS | 51022-70-9 |
|---|---|
| Molecular Formula | C13H23NO7S |
Tocris Bioscience™ Fexaramine
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CAS: 574013-66-4 Molecular Formula: C32H36N2O3
| CAS | 574013-66-4 |
|---|---|
| Molecular Formula | C32H36N2O3 |
Tocris Bioscience™ NS 9283
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Positive allosteric modulator of α4β2 nAChRs
| Inhibitors | NS 9283 |
|---|---|
| Product Type | NS 9283 |
| Molecular Weight (g/mol) | 248.24 |
| Purity | >99% |
Tocris Bioscience™ BAY 1816032
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Potent and selective BUB1 kinase inhibitor
Tocris Bioscience™ 4-Chlorophenylguanidine hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC Green Guides.
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Urokinase inhibitor
Tocris Bioscience™ TC SL C5
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Metastasis-associated lung adenocarcinoma transcript 1 (Malat1) RNA inhibitor
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H21N3O2 |
| Formula Weight | 323.4 |
Tocris Bioscience™ Thalidomide 5'-amine-alkylC8-amine
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Cereblon ligand with alkyl linker and terminal amine for onward chemistry
Tocris Bioscience™ SRT 1720
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Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis
| Target | Sirtuin 1/SIRT1 |
|---|---|
| CAS | 925434-55-5 |
| Purity | 0.98 |
| Chemical Name or Material | N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H23N7OS |
Tocris Bioscience™ (R)-(+)-Etomoxir sodium salt
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CAS: 828934-41-4 Molecular Formula: C15H19ClNaO4
| CAS | 828934-41-4 |
|---|---|
| Molecular Formula | C15H19ClNaO4 |
Tocris Bioscience™ BMS 193885
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CAS: 679839-66-8 Molecular Formula: C36H48N4O9
| CAS | 679839-66-8 |
|---|---|
| Molecular Formula | C36H48N4O9 |