Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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571
Tocris Bioscience™ UNC 2881
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent Mer kinase inhibitor
| CAS | 1493764-08-1 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-(Butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-N-[[4-(1H-imidazol-1-yl)phenyl]methyl]-5-pyrimidinecarboxamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C25H33N7O2 |
| Formula Weight | 463.58 |
572
| Shipping Condition | No special requirements |
|---|---|
| CAS | 481-49-2 |
| Color | White to Light-yellow to Beige |
| Purity | ≥94% |
| Physical Form | Crystalline Powder |
| Health Hazard 1 | Exclamation mark |
| Chemical Name or Material | Cepharanthine |
| Recommended Storage | Refrigerator +4°C |
| Molecular Formula | C37 H38 N2 O6 |
| Product Line | Life science |
573
Tocris Bioscience™ uPSEM 817 tartrate
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant
| Target | Pharmacologically Selective Effector Molecules/PSEM |
|---|---|
| CAS | 2341833-14-3 |
| Purity | 98% |
| Chemical Name or Material | 2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H19N3O.C4H6O6 |
| Formula Weight | 419.43 |
574
Tocris Bioscience™ AZD 8055
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Highly potent and selective mTOR inhibitor
| Target | mTOR Inhibitors |
|---|---|
| CAS | 1009298-09-2 |
| Purity | 0.98 |
| Chemical Name or Material | 5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H31N5O4 |
575
Tocris Bioscience™ LY 2109761
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective TGF-β kinase inhibitor
| Target | TGF-beta Receptor Inhibitors |
|---|---|
| CAS | 700874-71-1 |
| Purity | 0.98 |
| Chemical Name or Material | 4-[5,6-Dihydro-2-(2-pyridinyl)-4 H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]quinoline |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H27N5O2 |
576
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Thermo Scientific Chemicals Teriflunomide
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Thermo Scientific Chemicals Teriflunomide
CAS: 163451-81-8 Molecular Formula: C12H9F3N2O2
| CAS | 163451-81-8 |
|---|---|
| Molecular Formula | C12H9F3N2O2 |
577
Thermo Scientific Chemicals Levocetirizine dihydrochloride
CAS: 130018-87-0 Molecular Formula: C21H25ClN2O3·2HCl
| CAS | 130018-87-0 |
|---|---|
| Molecular Formula | C21H25ClN2O3·2HCl |
578
Tocris Bioscience™ AMG 900
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Potent pan-Aurora kinase inhibitor
| Target | Aurora Kinase Inhibitors |
|---|---|
| CAS | 945595-80-2 |
| Purity | 98% |
| Chemical Name or Material | N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C28H21N7OS |
579
Tocris Bioscience™ CX08005
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Competitive PTP1B inhibitor
| CAS | 1256341-22-6 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-[[[2-(Tetradecyl)phenyl]amino]carbonyl]benzoic acid |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C28H39N04 |
580
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Thermo Scientific Chemicals Telaprevir
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Thermo Scientific Chemicals Telaprevir
CAS: 402957-28-2 Molecular Formula: C36H53N7O6
| CAS | 402957-28-2 |
|---|---|
| Molecular Formula | C36H53N7O6 |
581
| Shipping Condition | No special requirements |
|---|---|
| CAS | 1441674-54-9 |
| Color | White to Yellow |
| Purity | ≥97.5% |
| Physical Form | Powder |
| Health Hazard 1 | Exclamation mark |
| Chemical Name or Material | Ledipasvir acetone |
| Recommended Storage | Normal conditions |
| Molecular Formula | C49 H54 F2 N8 O6 . C3 H6 O |
| Product Line | Life science |
582
Tocris Bioscience™ Z 944
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CaV3.x blocker
| CAS | 1199236-64-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-[[(3-Chloro-5-fluorobenzoyl)amino)methyl]-N-(1,1-dimethylethyl)-1-piperidineacetamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C19H27ClFN3O2 |
| Formula Weight | 383.89 |
583
Tocris Bioscience™ Avagacestat
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Highly potent γ-secretase inhibitor; orally bioavailable
| CAS | 1146699-66-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (2R)-2-[[(4-Chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide |
| Recommended Storage | Store at 4°C |
| Synonym | BMS-708163 |
| Molecular Formula | C20H17ClF4N4O4S |
| Formula Weight | 520.89 |
584
Tocris Bioscience™ Autophinib
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent VPS34 inhibitor
585
Tocris Bioscience™ SLM 6031434 hydrochloride
Greener Choice
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective sphingosine kinase 2 (Sphk2) inhibitor
| CAS | 1897379-34-8 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (2S)-2-[3-[4-(Octyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-pyrrolidinecarboximidamide hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H30F3N5O2.HCl |